SCI
10July
Bacterialandhostdeterminantsofcoughaerosolculturepositivityinpatientswithdrug-resistantversusdrug-susceptibletuberculosis
GrantTheron?,JasonLimberis?,RouxjeaneVenter?,LiezelSmithetal;Bacterialandhostdeterminantsofcoughaerosolculturepositivityinpatientswithdrug-resistantversusdrug-susceptibletuberculosis;NATUREMEDICINE;Publishedonline:29June
Correspondingauthor(s):KeertanDheda
Aburgeoningepidemicofdrug-resistanttuberculosis(TB)threatenstoderailglobalcontrolefforts.Althoughthemechanismsremainpoorlyclarified,drug-resistantstrainsarewidelybelievedtobelessinfectiousthandrug-susceptiblestrains.Consequently,wehypothesizedthatlowerproportionsofpatientswithdrug-resistantTBwouldhaveculturableMycobacteriumtuberculosisfromrespirable,cough-generatedaerosols